<160>What is the role of PrnP in mad cow disease? <161>What is the role of IDE in Alzheimer’s disease <162>What is the role of MMS2 in cancer? <163>What is the role of APC (adenomatous polyposis coli) in colon cancer? <164>What is the role of Nurr-77 in Parkinson’s disease? <165>How do Cathepsin D (CTSD) and apolipoprotein E (ApoE) interactions contribute to Alzheimer’s disease? <166>What is the role of Transforming growth factor-beta1 (TGF-beta1) in cerebral amyloid angiopathy (CAA)? <167>How does nucleoside diphosphate kinase (NM23) contribute to tumor progression? <168>How does BARD1 regulate BRCA1 activity? <169>How does APC (adenomatous polyposis coli) protein affect actin assembly <170>How does COP2 contribute to CFTR export from the endoplasmic reticulum? <171>How does Nurr-77 delete T cells before they migrate to the spleen or lymph nodes and how does this impact autoimmunity? <172>How does p53 affect apoptosis? <173>How do alpha7 nicotinic receptor subunits affect ethanol metabolism? <174>How does BRCA1 ubiquitinating activity contribute to cancer? <175>How does L2 interact with L1 to form HPV11 viral capsids? <176>How does Sec61-mediated CFTR degradation contribute to cystic fibrosis? <177>How do Bop-Pes interactions affect cell growth? <178>How do interactions between insulin-like GFs and the insulin receptor affect skin biology? <179>How do interactions between HNF4 and COUP-TF1 suppress liver function? <180>How do Ret-GDNF interactions affect liver development? <181>How do mutations in the Huntingtin gene affect Huntington’s disease? <182>How do mutations in Sonic Hedgehog genes affect developmental disorders? <183>How do mutations in the NM23 gene affect tracheal development? <184>How do mutations in the Pes gene affect cell growth? <185>How do mutations in the hypocretin receptor 2 gene affect narcolepsy? <186>How do mutations in the Presenilin-1 gene affect Alzheimer’s disease? <187>How do mutations in familial hemiplegic migraine type 1 (FHM1) gene affect calcium ion influx in hippocampal neurons?