Oxford Journals
Oxford University Press
Brigham and Women's Hospital, Renal Division, Boston, MA, USA Email: cmagee{at}partners.org
Sir,
As discussed by Sommerer et al. [1] in their recent comprehensive review of living kidney donation, a negative anti-donor T- and B-cell crossmatch is essential before proceeding with transplantation, but this is essential only immediately pretransplant. Successful desensitization to HLA antigensallowing subsequent transplantationis now being performed in many centres including our own with various combinations of intravenous IgG, plasmapheresis, mycophenolate mofetil and tacrolimus. Reported short and medium term outcomes are encouraging [2,3].
Conflict of interest statement. None declared.
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