TSH Receptor Mutation Database

Istvan T. Nebel, Dipl.-Inf.,, Barbara Trültsch, M.D., and Ralf Paschke, M.D.

University of Leipzig %D-04103 Leipzig, Germany

The increasing number of TSH receptor mutations has stimulated us to establish a TSH receptor mutation database that is accessible via the internet (http://www.uni-leipzig.de/~innere/TSH). This database describes all published activating and inactivating TSH receptor germline mutations.

The clinical data on the patients will increase with time, and more mutations will be identified. To add further not yet published information the database also invites comments that will be used to complete and improve the database. We therefore invite the scientific community to use and further improve this TSH receptor mutation database.

Footnotes

Received February 22, 1999. Address correspondence to: Ralf Paschke, Department of Internal Medicine III, University of Leipzig, Philip-Rosenthal-Strasse 27, Leipzig D-04103, Germany.