From the Editor-in-Chief

John P. Bilezikian, M.D., Editor-in-Chief

Obesity is the main theme of the 86th Annual Meeting of The Endocrine Society. Chip Ridgeway, our President, has indeed selected a worthy topic. Obesity has slowly but also rather dramatically appeared on the medical scene with ominous implications for the health of our civilization. There are now more overweight than underweight individuals in the world. The societal, political, economic, and healthcare consequences of an overweight society have enormous implications. It is thus fitting for our meeting to devote attention to this subject. As is traditional, the theme of the annual meeting of The Endocrine Society is also the theme of The Society Journals’ June issues. In this issue of JCEM, we are pleased to present to you a series of special features written by great authorities in the field. In the Special Features section of JCEM, you will find 14 articles written by experts on epidemiology, mechanisms and molecules, regulation of body weight, concomitants of obesity, and therapeutic approaches to obesity. Epidemiological considerations are the focus of articles by Cynthia J. Stein and Graham A. Colditz (The Epidemic of Obesity), Svetlana Ten and Noel Maclaren (Insulin Resistance Syndrome in Children), and Arnold H. Slyper (The Pediatric Obesity Epidemic). For mechanisms and molecules, Erin E. Kershaw and Jeffrey S. Flier write on Adipose Tissue as an Endocrine Organ, whereas Anthony P. Coll, I. Sadaf Farooqi, Benjamin G. Challis, Giles S. H. Yeo, and Stephen O’Rahilly consider the genetics of Proopiomelanocortin and Energy, and Barry J. Goldstein and Rosario Scalia focus upon Adiponectin. The regulation of body weight is the subject of articles by Antony D. Karelis, David H. St-Pierre, Florence Conus, Remi Rabasa-Lhoret, and Eric T. Poehlman (Metabolic and Body Composition Factors in Subgroups of Obesity: What Do We Know?) and by Katie Wynne, Sarah Stanley, and Steve Bloom (The Gut and Regulation of Body Weight). Concomitant issues along with comorbidities of obesity are considered in articles by George A. Bray (Medical Consequences of Obesity), Nicole Cossrow and Bonita Falkner (Race/Ethnic Issues in Obesity and Obesity-Related Comorbidities), Scott M. Grundy (Obesity, Metabolic Syndrome, and Cardiovascular Disease), and Molly C. Carr and John D. Brunzell (Abdominal Obesity and Dyslipidemia in the Metabolic Syndrome). Therapeutic approaches to obesity are the focus of articles by Judith Korner and Louis J. Aronne (Pharmacological Approaches to Weight Reduction) and by David E. Cummings, Joost Overduin, and Karen E. Foster-Schubert (Gastric Bypass for Obesity).

The Journal also features this month original articles on obesity. They are identified in the Table of Contents immediately after the Special Features section and before the Endocrine Care Section. In this section, you will find 16 articles including those devoted to epidemiology, genetics, growth and development, and regulatory molecules. Original articles on obesity also focus upon expressions of weight loss with regard to enzymatic control, hormonal and metabolic changes, and body composition. A Rapid Communication by G. Milan, E. Dalla Nora, C. Pilon, C. Pagano, M. Granszotto, M. Manco, G. Mingrone, and R. Vettor considers Changes in Muscle Myostatin Expression in Obese Subjects after Weight Loss. Throughout the year, a number of other special features and original articles on the subject of obesity will be published.

We trust that you will find this special issue of JCEM to be of particular interest.





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