ERK5 and ERK2 cooperate to regulate NF-kappa B and cell transformation.

Gray Pearson, Jessie M. English, Michael A. White, and Melanie H. Cobb

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Fig. 5.   Coexpression of MEK5DD and ERK5 activates NF-kappa B. NIH3T3 cells were transfected with cDNAs encoding the NF-kappa B reporter, along with control vector, MEK5DD, ERK5, or MEK5DD and ERK5 together. Shown is the average of three independent experiments performed in duplicate. Transfection efficiency and relative activity were determined as described for Fig. 2.





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