Vol 269, p. 9052
Page 9053: A detailed study of the minimal sequence requirement for topoisomerase III cleavage, using progressively smaller oligonucleotides surrounding the cleavage site presented in this manuscript, has revealed that the cleavage site was incorrectly placed. Rather than
5`-CAGAATCAGAATGAGCCGCAACTTCGGGATGAAAATGCTCACAAT-3`,
the correct site of cleavage should be indicated as follows:
5`-CAGAATCAGAATGAGCCGCAACTTCGGGATGAAAATGCTCACAAT-3`,
where
indicates the site of cleavage. Cleavage of the oligonucleotide
by topoisomerase III results in the production of a 5`-radiolabeled
23-base product rather than the 24-base product indicated in the text
and the legend of Fig. 6. This observation, however, does not alter the
conclusions of the paper.