Mersey Care NHS Trust, Waterloo Day Hospital, Park Road, Waterloo, Liverpool L22 3XR, UK
I read Dr Stewart's article on vascular dementia (Stewart, 2002) with great interest. As a recently appointed consultant in old age psychiatry (having been trained in the old way about diagnosing vascular dementia, i.e. sudden onset, stepwise deterioration, history of vascular risk factors, etc.), I started noticing a very different presentation of vascular dementia, especially in those with evidence of extensive periventricular disease on computed tomography. These cases commonly present with a range of frontal executive function deficits, with functional psychiatric symptoms of anxiety and depression and sometimes with progressive aphasia, and do not necessarily have the classical history of vascular dementia as described in textbooks.
The importance of the clinical findings is that as clinicians and educational supervisors we need to use more screening tests for frontal executive functions in routine assessments of dementia. In addition to the Mini-Mental State Examination (Folstein et al, 1975), verbal fluency and similarities (FAS; Thomas & O'Brien, 2002) tests are quick ways of testing frontal functions and should be encouraged among all members of a multi-disciplinary team. This has also been recognised in the new Cambridge Examination for Mental Disorder of the Elderly, Revised (CAMDEX-R; Roth et al, 1999).
Findings of periventricular ischaemia are controversial as far as their relevance to dementia diagnosis is concerned but patients who present with marked frontal functioning deficit and evidence of periventricular ischaemia on computed tomography should receive a diagnosis of vascular dementia. It is now known that ischaemia in periventricular areas interferes with the corticostriatothalamocortical loops which, in turn, affect functioning of frontal lobes.
REFERENCES
Folstein, M. F., Folstein, S. E. & McHugh, P. R. (1975) Mini-Mental State: a practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12, 189-198.[CrossRef][Medline]
Roth, M., Huppert, P. A., Mountjoy, C., et al (1999) Cambridge Examination for Mental Disorder of the Elderly, Revised. Cambridge: Cambridge University Press.
Stewart, R. (2002) Vascular dementia: a
diagnosis running out of time. British Journal of
Psychiatry, 180,
152-156.
Thomas, A. J. & O'Brien, J. T. (2002) Alzheimer's disease. In Psychiatry in the Elderly (eds R. Jacoby & C. Oppenheimer), pp. 513-514. Oxford: Oxford University Press.
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