1	355	12393889	J Biol Chem 2002 Dec 27;277(52):50907-13.	A novel signaling mechanism shows synergy with anti-CD95 monoclonal antibodies for apoptosis and NF-kappaB nuclear translocation.
2	355	12324452	J Biol Chem 2002 Dec 6;277(49):47826-33.	Fas induces alpha(v)beta(8) integrin in cell migration
3	355	12221075	J Biol Chem 2002 Nov 8;277(45):42867-74.	Glutathione peroxidase-1 protects from apoptosis induced by this antigen
4	355	12196516	J Biol Chem 2002 Oct 25;277(43):40760-7.	signals to mitochondria via FADD, caspase-8/10, Bid, and Bax but differentially regulate events downstream from truncated Bid compared to TRAIL receptor 2
5	355	12107169	J Biol Chem 2002 Sep 13;277(37):34343-8.	the death effector domain of FADD is involved in interaction with Fas.
6	355	12177303	Nucleic Acids Res 2002 Aug 15;30(16):3609-14.	In the case of Fas-mediated apoptosis, when we transiently introduced these hybrid-ribozyme libraries into Fas-expressing HeLa cells, we were able to isolate surviving clones that were resistant to or exhibited a delay in Fas-mediated apoptosis
7	581	12023951	J Biol Chem 2002 Aug 2;277(31):27912-8.	activation during apoptosis due to oxidative stress in cells expressing wild-type and mutant cystic fibrosis transmembrane conductance regulator
8	581	12393866	J Biol Chem 2002 Dec 20;277(51):49569-76.	Regulation of intracellular pH mediates Bax activation in HeLa cells treated with staurosporine or tumor necrosis factor-alpha
9	581	12393884	J Biol Chem 2002 Dec 27;277(52):50834-41.	Apocytochrome c blocks caspase-9 activation and Bax induced apoptosis
10	581	12151395	J Biol Chem 2002 Oct 4;277(40):37949-54.	Inactivation of p21WAF1 sensitizes cells to apoptosis via an increase of both p14ARF and p53 levels and an alteration of this protein and Bcl-2 ratio
11	650	12082094	J Biol Chem 2002 Sep 13;277(37):33545-58.	induces osteocalcin expression in osteoblasts
12	1026	12058028	J Biol Chem 2002 Aug 16;277(33):29792-802.	stabilization by phosphorylation influenzed by protein kinase p38 alpha and JNK1
13	1026	12388558	J Biol Chem 2002 Dec 13;277(50):47976-9.	role of PIN1 in transactivation
14	1026	12354776	J Biol Chem 2002 Dec 6;277(49):47338-47.	Cleavage of p21waf1 by proteinase-3, a myeloid-specific serine protease, potentiates cell proliferation
15	1026	12151395	J Biol Chem 2002 Oct 4;277(40):37949-54.	inactivation sensitizes cells to apoptosis via an increase of both p14ARF and p53 levels and an alteration of the Bax/Bcl-2 ratio
16	1026	12138103	J Biol Chem 2002 Sep 27;277(39):36329-37.	transcriptional regulation of p21 CIP1 WAF1 controls p53 independent ovarian cancer apoptosis
17	1026	12145325	Proc Natl Acad Sci U S A 2002 Aug 6;99(16):10683-8.	C/EBPalpha is essential for p21-mediated inhibition of G1 to S-phase progression by RAP in KSHV-infected host cells
18	1291	11973338	J Biol Chem 2002 Jul 26;277(30):26872-8.	keratinocyte growth factor (KGF), a key stimulator of epithelial cell proliferation during wound healing, preferentially binds to collagens I, III, and VI.
19	1581	12011083	J Biol Chem 2002 Jul 26;277(30):26804-7.	regulation of CYP7A1 and CYP27A1 in human liver
20	1581	12202481	J Biol Chem 2002 Nov 8;277(45):42588-95.	data suggest that the lack of an LXR element in the region from -56 to -49 of the human CYP7A1 promoter may account for some of the differences in response to diets between humans and rodents
21	1869	12077144	J Biol Chem 2002 Aug 30;277(35):31679-93.	conclude that E2F proteins and Sp1 play an important role in the control of p18 expression
22	1869	12149244	J Biol Chem 2002 Oct 18;277(42):39760-8.	E2F-1 regulates the expression of APAF-1 in human cells
23	1977	12138083	J Biol Chem 2002 Sep 6;277(36):32855-9.	eIF4E phosphorylation during hypertonic shock is not required for protein synthesis
24	1977	12105188	J Cell Biol 2002 Jul 8;158(1):165-74.	role of integrin (alpha 6 beta 4)in the regulation of eIF-4E activity and VEGF translation in breast carcinoma cells
25	2065	12411582	Proc Natl Acad Sci U S A 2002 Nov 12;99(23):14843-8.	Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of this epidermal growth factor receptor family member
26	2252	11973338	J Biol Chem 2002 Jul 26;277(30):26872-8.	keratinocyte growth factor (KGF), a key stimulator of epithelial cell proliferation during wound healing, preferentially binds to collagens I, III, and VI.
27	2252	12215437	J Biol Chem 2002 Nov 8;277(45):42815-20.	activity is potentiated by dermatan sulfate binding
28	2688	11994274	J Biol Chem 2002 Jul 19;277(29):26662-72.	report that autocrine hGH production by mammary carcinoma cells specifically results in the transcriptional repression of the p53-regulated placental transforming growth factor-beta gene (Placental growth factor-beta; TGF-beta)
29	2741	12239220	J Biol Chem 2002 Nov 22;277(47):44845-53.	Results provide evidence for a conserved pore opening mechanism in anion-selective members of the ligand-gated ion channel family, including glycine receptors (GlyR) and gamma-aminobutyric acid, type A receptors (GABA(A)R).
30	3562	12093816	J Biol Chem 2002 Oct 11;277(41):38764-71.	Data suggest that increased activity of mutated interleukin 3 is due to a change from a rare ligand to a common one, allowing the increase in IL-3-dependent signaling.
31	3621	12015309	J Biol Chem 2002 Aug 16;277(33):29832-9.	role in differential regulation of histone acetylation
32	3717	12351625	J Biol Chem 2002 Dec 6;277(49):47954-63.	the JH2 domain contributes to both the uninduced and ligand-induced Jak-receptor complex, where it acts as a cytokine-inducible switch to regulate signal transduction
33	3949	12036962	J Biol Chem 2002 Aug 9;277(32):29172-80.	apoE binds to the LDL receptor by interacting with more than one of the receptor ligand-binding repeats.
34	3949	12221107	J Biol Chem 2002 Nov 15;277(46):44044-9.	ARH functions as an adaptor protein that couples LDLR to the endocytic machinery
35	3949	12149270	J Biol Chem 2002 Oct 4;277(40):37229-34.	bile acids affect gene expression via a MAPK cascade-mediated stabilization of mRNA
36	3973	12091390	J Biol Chem 2002 Sep 6;277(36):33431-8.	HDAC-Sin3A complex regulates LHR Gene transcription
37	4012	12080061	J Biol Chem 2002 Aug 30;277(35):31887-92.	Identification of a tankyrase-binding motif in this protein
38	4217	12189133	J Biol Chem 2002 Oct 25;277(43):40703-9.	role in activating the JNK and p38 MAP kinase cascades in response to environmental stresses such as reactive oxygen species
39	4851	12065598	J Biol Chem 2002 Aug 16;277(33):29760-4.	acid alpha-glucosidase gene is a novel target of the Notch-1/Hes-1 signaling pathway
40	5468	12015306	J Biol Chem 2002 Jul 26;277(30):26821-30.	PPRE in intron 1 of the ACBP gene is a bona fide PPARgamma-response element.
41	5468	12189136	J Biol Chem 2002 Oct 25;277(43):40549-56.	role of 13-(S)-HODE in upregulating the MAP kinase signaling pathway and subsequently downregulating PPARgamma
42	5468	12107164	J Biol Chem 2002 Sep 13;277(37):34176-81.	Activation of endothelial PPAR-gamma has a potent anti-inflammatory role.
43	5468	12077117	J Biol Chem 2002 Sep 6;277(36):33153-63.	85kD PLA2 mediates PPARG activation in lung epithelial cells
44	5468	12397176	Proc Natl Acad Sci U S A 2002 Nov 12;99(23):15072-7.	mediates the proliferative action of mast-cell tryptase: possible relevance to human fibrotic disorders
45	5581	12198125	J Biol Chem 2002 Nov 1;277(44):41850-6.	activation inhibited TNF-induced apoptosis in MCF-7 cells
46	5581	12185081	J Biol Chem 2002 Oct 25;277(43):40449-55.	role in regulating caveolin-1 expression and secretion
47	5581	12121973	J Biol Chem 2002 Sep 20;277(38):35305-13.	promotes survival of lung cancer cells by suppressing apoptosis through dysregulation of the mitochondrial caspase pathway
48	5624	12063259	J Biol Chem 2002 Aug 9;277(32):28836-40.	identifies FVa binding site in the positive exosite of APC that is primarily involved in binding and cleaving at Arg(506) on FVa
49	5624	12029084	J Biol Chem 2002 Aug 9;277(32):28987-95.	X-ray crystallography of Activated Protein C
50	5624	12407115	J Biol Chem 2002 Dec 20;277(51):49815-9.	thrombomodulin-dependent activation of protein C is regulated by Smad6 and Smad7
51	5728	12177006	J Biol Chem 2002 Oct 25;277(43):40247-52.	search for potential PTEN modulators through protein-protein interaction
52	5879	12377770	J Biol Chem 2002 Dec 13;277(50):48379-85.	role in pathway that promotes urokinase plasminogen activator mRNA stability in invasive breast cancer cells
53	5879	12376551	J Biol Chem 2002 Dec 6;277(49):47810-7.	Rac1 and Cdc42 are activated independent of RhoG
54	5879	12239215	J Biol Chem 2002 Nov 22;277(47):44988-95.	Data show that arsenic trioxide induces activation of the small G-protein Rac1 and the alpha and beta isoforms of the p38 mitogen-activated protein (MAP) kinase in several leukemia cell lines.
55	6385	12377772	J Biol Chem 2002 Dec 20;277(51):49296-303.	SDC4 regulates inositol phospholipid binding and signaling
56	6506	11994293	J Biol Chem 2002 Jul 19;277(29):26074-80.	Reentrant loop II of the GLT-1 transporter forms part of an aqueous pore, the access of which is blocked by the glutamate analogue dihydrokainate, and that sodium influences the conformation of this pore-loop.
57	6667	12077144	J Biol Chem 2002 Aug 30;277(35):31679-93.	conclude that E2F proteins and Sp1 play an important role in the control of p18 expression
58	6667	12052832	J Biol Chem 2002 Aug 9;277(32):28815-22.	demonstrates role of the Sp1 protein in basal and estrogen-induced growth and gene expression in breast cancer
59	6667	12359731	J Biol Chem 2002 Dec 13;277(50):48333-41.	role in regulating megakaryocyte-specific glycoprotein VI promoter
60	6667	12324467	J Biol Chem 2002 Dec 6;277(49):47541-50.	there is a mechanically coupled transcriptional circuit that promotes binding of p38 to Sp1 in the nucleus
61	6667	12228247	J Biol Chem 2002 Nov 15;277(46):43799-808.	Sp1 regulates basal endoglin transcription in human and mammalian cells
62	6667	12228234	J Biol Chem 2002 Nov 15;277(46):43873-80.	Sp1 regulates human reduced folate carrier gene expression
63	6667	12186868	J Biol Chem 2002 Nov 15;277(46):43903-17.	TGF-beta1 inhibition of COL2A1 gene transcription in articular chondrocytes is mediated by an increase of the Sp3/Sp1 ratio and by the repression of Sp1 transactivating effects on that gene
64	6667	12151407	J Biol Chem 2002 Oct 11;277(41):38230-8.	Results suggest that Sp1 and Sp3 associate with the hTERT promoter, recruiting HDAC for the localized deacetylation of nucleosomal histones and transcriptional silencing of the hTERT gene in normal human somatic cells
65	6667	12169688	J Biol Chem 2002 Oct 18;277(42):39082-92.	Sp1 plays a role in regulation of promoter activity and in PKA-mediated expression of mitochondrial serine:pyruvate aminotransferase
66	6667	12105191	J Biol Chem 2002 Sep 13;277(37):33833-41.	The hexosamine pathway regulates the plasminogen activator inhibitor-1 gene promoter and Sp1 transcriptional activation through protein kinase C-betaI and -delta.
67	6667	11970950	J Biol Chem 2002 Sep 27;277(39):36244-52.	Ets-1 and Sp1 have a role in regulating FasL expression in human vascular smooth muscle cells
68	7066	12359731	J Biol Chem 2002 Dec 13;277(50):48333-41.	induces megakaryocyte-specific glycoprotein VI promoter and its regulation by GATA-1, Fli-1, and Sp1
69	7077	12374789	J Biol Chem 2002 Dec 13;277(50):48696-707.	investigation of structural and functional differences between TIMP-4 and TIMP-2 by mutagenesis into C-terminal tails
70	7421	11991950	J Biol Chem 2002 Jul 12;277(28):25125-32.	regulates expression of CYP3A4, CYP2B6, and CYP2C9 in hepatocytes
71	7508	12177305	Nucleic Acids Res 2002 Aug 15;30(16):3624-31.	human XPC DNA repair gene: arrangement, splice site information content and influence of a single nucleotide polymorphism in a splice acceptor site on alternative splicing and function
72	7508	12242345	Proc Natl Acad Sci U S A 2002 Oct 1;99(20):12985-90.	XPC is regulated by DNA damage and p53
73	8565	12016229	J Biol Chem 2002 Aug 9;277(32):28394-9.	the KMSSS sequence in human tyrosyl-tRNA synthetase stabilizes the transition state for the tyrosine activation reaction by interacting with the pyrophosphate moiety of ATP
74	8565	12427973	Proc Natl Acad Sci U S A 2002 Nov 26;99(24):15369-74.	The structure of human mini-TyrRS containing both the catalytic & the anticodon recognition domains, is reported to a resolution of 1.18 A. The spatial disposition of the anticodon recognition domain relative to the catalytic domain is unique.
75	8728	12393862	J Biol Chem 2002 Dec 13;277(50):48514-22.	investigation of proteolytic activity
76	8728	12006600	J Biol Chem 2002 Jul 12;277(28):25583-91.	activation by furin via one of two consecutive recognition sites
77	9961	12177006	J Biol Chem 2002 Oct 25;277(43):40247-52.	identification as a dominant PTEN-binding protein in a yeast two-hybrid screen
78	11622	12215427	J Biol Chem 2002 Nov 15;277(46):44028-34.	Nedd8 and AhR localize to overlapping areas in the heart and spinal ganglia, raising the possibility that this interaction may play a role in organogenesis
79	11622	12107286	Proc Natl Acad Sci U S A 2002 Jul 23;99(15):9990-5.	induces stomach tumors when constitutively active
80	11820	12239221	J Biol Chem 2002 Dec 6;277(49):47373-9.	inflammatory effects of beta-amyloid are mediated by CD36-initiated signal transduction
81	11820	12087104	J Biol Chem 2002 Sep 27;277(39):36415-24.	APP localizes to cell membrane after calpain inhibition
82	11820	12068009	J Biol Chem 2002 Sep 6;277(36):33012-7.	Brain neuron degeneration increases in transgenic mice expressing a Alzheimer's disease mutation (Swedish mutations of amyloid precursor protein)
83	11852	12384510	J Biol Chem 2002 Dec 20;277(51):49389-96.	RhoB isoprenylation is necessary for its rapid turnover; there is a link between the cholesterol biosynthetic pathway and the regulation of G-protein expression
84	12043	12167626	J Biol Chem 2002 Oct 11;277(41):38676-82.	Results suggest that Bcl-2 activates NF-kappa B by a signaling mechanism that involves Raf-1/MEKK-1 mediated activation of IKK beta.
85	12487	12077322	Proc Natl Acad Sci U S A 2002 Jul 9;99(14):9369-73.	CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse.
86	12914	12407098	J Biol Chem 2002 Dec 27;277(52):50535-42.	Insulin-like growth factor-1 increases skeletal muscle dihydropyridine receptor alpha and shows transcriptional activity by acting on an element of the promoter region
87	12914	11943779	J Biol Chem 2002 Jul 5;277(27):24081-9.	co-activation of crystallin gene expression
88	12914	12165570	Proc Natl Acad Sci U S A 2002 Aug 20;99(17):11435-40.	Activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli.
89	12914	12397173	Proc Natl Acad Sci U S A 2002 Nov 12;99(23):14789-94.	has a distinct role in hematopoietic stem cell self-renewal
90	13131	12244214	Proc Natl Acad Sci U S A 2002 Oct 1;99(20):13178-83.	Disabled 1 is is affected by Reelin and plays a role in glial differentiation and forebrain development through beta1-integrin dependent signal transduction
91	14235	12221098	J Biol Chem 2002 Nov 15;277(46):44310-6.	restoring FoxM1B expression in old-aged mice caused elevated levels of Cyclin B1, Cyclin B2, Cdc25B, Cdk1, and p55CDC mRNA as well as stimulating Cdc25B nuclear localization during liver regeneration, all of which are required for mitosis
92	14235	12482952	Proc Natl Acad Sci U S A 2002 Dec 24;99(26):16881-6.	Foxm1b transcription factor regulates expression of cell cycle proteins essential for hepatocyte entry into DNA replication and mitosis.
93	14674	12183468	J Biol Chem 2002 Oct 18;277(42):39493-8.	G12/G13 activates Gi-mediated signaling pathways which are sufficient to induce integrin alpha(IIb)beta3 activation
94	14674	12077299	Proc Natl Acad Sci U S A 2002 Jul 9;99(14):9352-7.	The G alpha(12)-mediated signaling pathway functionally interacts not only with the G alpha(13)- but also with the G alpha(q/11)-mediated signaling systems.
95	16438	12118121	Proc Natl Acad Sci U S A 2002 Jul 23;99(15):9830-5.	Bcl-X(L) affects Ca(2+) homeostasis by altering its expression
96	17246	12232053	Proc Natl Acad Sci U S A 2002 Oct 1;99(20):13125-30.	MDM2 is not required for p53 proteasomal degradation regulated by NADPH quinone oxidoreductase 1
97	18046	12167641	J Biol Chem 2002 Oct 18;277(42):39769-76.	NF-Y binds to p73 and transcriptionally regulates platelet derived growth factor beta receptor
98	19013	12176975	J Biol Chem 2002 Dec 27;277(52):50237-44.	influences substrate utilization for hepatic glucose production
99	19013	12118038	J Biol Chem 2002 Jul 19;277(29):26089-97.	redundancy in the functions of PPARs alpha and delta as transcriptional regulators of fatty acid homeostasis and suggest that in skeletal muscle high levels of the delta-subtype can compensate for deficiency of PPAR alpha
100	19246	12169659	Proc Natl Acad Sci U S A 2002 Aug 20;99(17):11357-62.	findings suggest that PTP1B modulates insulin signaling in liver and fat, and that therapeutic modalities targeting PTP1B inhibition may have clinical benefit in type 2 diabetes
101	20387	12015304	J Biol Chem 2002 Jul 26;277(30):26971-9.	the N terminus of SP-D 1) can functionally replace the N terminus of SP-A for lipid aggregation and tubular myelin formation and is not sufficient to reverse the structural and metabolic pulmonary defects in the SP-D(-/-) mouse
102	20852	12023955	J Biol Chem 2002 Jul 26;277(30):27169-75.	The anti-apoptotic activity of IL-4 in B cells is mediated through the activation of Stat6 and subsequent transcription of Bcl-xL.
103	20852	12215441	J Biol Chem 2002 Nov 8;277(45):42821-9.	involved with TH2 cytokines and allergic challenge to induce Ym1 expression in macrophages
104	20852	12121972	J Biol Chem 2002 Sep 27;277(39):36563-9.	STAT6 is required for IL-4 signal transduction
105	20852	12151598	Proc Natl Acad Sci U S A 2002 Aug 20;99(17):11340-5.	Not involved in il-18 contribution to the spontaneous development of atopic dermatitis-like inflammatory skin lesions
106	21473	12082183	Proc Natl Acad Sci U S A 2002 Jul 9;99(14):9374-9.	method for identifying both the alpha- and beta-chains of the T cell receptor (TCR) from individual pancreatic islet-infiltrating T cells at the earliest stages of disease in nonobese diabetic mice (NOD)
107	23221	12370419	Proc Natl Acad Sci U S A 2002 Oct 15;99(21):13647-52.	A previously uncharacterized gene, DBC2 (deleted in breast cancer), was cloned from a homozygously deleted region at human chromosome 8p21.
108	24166	12122016	J Biol Chem 2002 Sep 27;277(39):36863-71.	data suggest that TTF-1 plays an important regulatory role in the gene transcription for pituitary adenylate cyclase-activating polypeptide
109	24707	12186877	J Biol Chem 2002 Nov 1;277(44):41693-700.	Retinoic acid receptor plays a significant role in retinoic acid induced MKP-1 transcription.
110	24835	12130632	J Biol Chem 2002 Sep 20;277(38):35150-5.	role in inducing matrix metalloproteinase-9 gene
111	24835	12118012	J Biol Chem 2002 Sep 27;277(39):36443-8.	TNFalpha has a role in ganglioside GD3 transport to mitochondria in rats
112	25302	12244045	J Biol Chem 2002 Nov 22;277(47):44920-4.	Results suggest that nicotine stimulation of alpha7 nicotinic acetylcholine receptor (nAChR) transduces signals to phosphatidylinositol 3-kinase and Akt via Janus kinase 2 (JAK2) in a cascade, which results in neuroprotection.
113	25522	12130632	J Biol Chem 2002 Sep 20;277(38):35150-5.	role in regulating transcription of the matrix metalloproteinase-9 gene induced by IL-1 and TNF-alpha in glioma cells via NF-kappa B
114	25522	12095990	J Biol Chem 2002 Sep 6;277(36):32915-22.	Fatty acid infusion impairs insulin stimulated PKC activation
115	29715	12118014	J Biol Chem 2002 Sep 13;277(37):33957-62.	aspartic acid 610 and lysine 617 (using the rat NCX1.4 numbering scheme) are critical molecular determinants of the unique Ca(2+) regulatory properties of NCX1.4.
116	36054	12084706	J Biol Chem 2002 Aug 9;277(32):28372-5.	results suggest that Wengen can act as a component of a functional receptor for Eiger
117	37386	12393817	Proc Natl Acad Sci U S A 2002 Nov 12;99(23):14813-8.	mediates cell adhesion and is essential for maintaining somatic stem cells in the Drosophila ovary
118	39753	12397080	J Biol Chem 2002 Dec 20;277(51):49644-50.	DIAP1 is required to prevent excess accumulation of the first form of processed DRONC, presumably through its ability to act as a ubiquitin-protein ligase
119	40670	12215430	J Biol Chem 2002 Nov 15;277(46):44366-75.	expressed and characterized Drosophila PI4KII and its catalytic domain
120	42896	12213838	J Cell Biol 2002 Sep 2;158(5):941-51.	Crumbs interacts with moesin and beta(Heavy)-spectrin in the apical membrane skeleton of Drosophila.
121	50592	12368290	J Biol Chem 2002 Dec 6;277(49):47765-9.	a short sequence present in the N-terminal domain has a role in controlling anterograde trafficking of ionotropic glutamate receptors
122	50800	12177004	J Biol Chem 2002 Oct 18;277(42):39561-5.	liver X receptors regulate phospholipid transfer protein in mice
123	54226	12093789	J Cell Biol 2002 Jul 8;158(1):79-89.	A novel mechanism for the regulation of amyloid precursor protein metabolism.
124	54226	12244210	Proc Natl Acad Sci U S A 2002 Oct 1;99(20):13217-21.	amyloid-beta protein has a role as an inactivator of protein kinase A and decreases CREB phosphorylation
125	54315	12372827	J Biol Chem 2002 Dec 6;277(49):47129-35.	superoxide (or its products) exerts its uncoupling effect by activating the proton transport mechanism of UCP2 at the matrix side of the mitochondrial inner membrane
126	56172	12185249	Proc Natl Acad Sci U S A 2002 Sep 3;99(18):11890-5.	ANKH is upregulated by androgen in the LNCaP prostate cell line.
127	79083	11980908	J Biol Chem 2002 Jul 12;277(28):25423-30.	links rab27a and myosin Va function in melanosome transport
128	79083	12221080	J Biol Chem 2002 Nov 8;277(45):43096-103.	The C-terminus of Slac2-a/melanophilin contains a novel actin-binding site, which may be involved in capture of Rab27-containing organelles in the actin-enriched cell periphery.
129	79083	12189142	J Biol Chem 2002 Oct 18;277(42):40118-24.	SHD1 of Slac2-a/melanophilin alone is both necessary and sufficient for high affinity specific recognition of the GTP-bound form of Rab27A
130	81504	12084708	J Biol Chem 2002 Sep 20;277(38):35282-8.	signal transduction through tyrosine-phosphorylated C-terminal fragments of amyloid precursor protein via an enhanced interaction with Shc/Grb2 adaptor proteins in reactive astrocytes of Alzheimer's disease brain
131	81668	12050161	J Biol Chem 2002 Aug 30;277(35):32099-108.	results indicate that the GnRH receptor activates both G(q) and G(s) signaling to regulate gene expression in L beta T2 cells
132	116590	12161450	J Biol Chem 2002 Aug 9;277(32):28384-93.	Acute GH induced phosphorylation of ERK1/2; this induction was inhibited by prior exposure to GH
133	116590	12393899	J Biol Chem 2002 Dec 20;277(51):49577-84.	ERK1/2 and PI3K may protect neurons from apoptosis by inhibiting GSK3beta
134	116590	12213812	J Biol Chem 2002 Nov 8;277(45):42830-40.	mediates serotonin-induced MMP-13 production in rat uterine smooth muscle cells
135	116590	12087100	J Biol Chem 2002 Sep 13;277(37):33676-82.	Interleukin-22 (IL-22) activates the JAK/STAT, ERK, JNK, and p38 MAP kinase pathways in a rat hepatoma cell line.
136	116590	12121979	J Biol Chem 2002 Sep 27;277(39):35819-25.	ERK2 is regulated by the dopaminergic D2 receptor in the rat pituitary
137	2065	12154198	Science 2002 Aug 23;297(5585):1330-3.	structure reveals a contact between domains II and IV that constrains the relative orientations of ligand-binding domains
138	3949	12459547	Science 2002 Dec 20;298(5602):2353-8.	crystal structure of the extracellular portion of LDL-R at pH = 5.3 and at 3.7    resolution; this structure should represent the conformation of LDL-R adopted in endosomes
139	3949	12493918	Science 2002 Dec 20;298(5602):2401-3.	productive LDL-R folding in a cell is not vectorial but is mostly posttranslational, and involves transient long-range non-native disulfide bonds that are isomerized into native short-range cysteine pairs